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Lavender oil protects the liver and kidneys against oxidative stress

A new study reports that lavender oil protects the liver and kidneys against oxidative stress, caused by a poisonous chemical like Malathion. The research was conducted by Tunisian researchers.

They tested the essential oil of Spanish lavender (Lavandula stoechas) for its hepatoprotective and nephroprotective potential against Malathion.

Lavender contains volatile compounds which possess a characteristic, pleasant odor. Furthermore, it has therapeutic properties and shows an important antioxidant activity.

Malathion is a common insecticide. It belongs to the family of organophosphate. Malathion is often used in both household and agricultural areas. Though touted to be protected among organophosphates, Malathion remains a very effective neurotoxin. It can kill insects but at the same time causes significant harm to the liver and kidneys of mammalian species.

On entering into the body, Malathion breaks down into malaoxon. Malaoxon is an even more toxic metabolite than the parent chemical. Upon reaching the liver and kidneys, it causes oxidative stress. This stress damages the organs.

Antioxidants can be used to avoid such corporal oxidative anxiety. Many types of research link Lavender to have such antioxidant properties.

The antioxidant potential of lavender

Researchers from the Faculty of Sciences of Tunis (FST) observed the heap-protective and nephroprotective activities of lavender oil. An animal study was set up using 96 young male mice. They separated them into eight groups which received varied treatments.

1. The control group; it was assisted as an untreated baseline.
2. The Malathion group; it received 200 milligrams per kilogram (mg/kg) of the organophosphate every day.
3. Three of the groups; were given 10, 30, and 50 mg/kg of lavender essential oil.
4. The last three groups; were given a combination of essential oil and Malathion treatment.

The test continued for 30 days. Then, the animals were observed for the signs of body weight gain and other effects.

After the experiment, the mice were sacrificed. Their kidneys and liver were picked for a study of the morphological and chemical changes made by the Malathion and lavender essential oil.

Protect your liver and kidneys

The FST investigators exposed that Malathion caused antagonistic effects in the mice. These animals did not increase as much body weight from eating the same as untreated mice. At the same time, the kidneys and liver of the malathion-exposed mice increase in size. Hence, this swelling distressed the proper blood flow through these organs.

Furthermore, these mice also exposed a significant disturbance in their metabolism. This disturbance caused many damaging effects on their health.

The management of Malathion to the animals showed a consistent upsurge in their oxidative anxiety levels. However, the concentration of hydrogen peroxide and malondialdehyde were seen to upsurge speedily.

Also, the activity levels of the antioxidant enzymes catalase and glutathione peroxidase went down. The superoxide dismutase (SOD) enzymes were also affected. Hence, the levels of copper-SOD, manganese-SOD, and iron-SOD in the kidneys and liver lessened.

These antioxidant enzymes failure exposed that Malathion exerted harmful oxidative stress against these organs.

However, lavender oil can back almost all of the negative effects of Malathion exposure. Mice treated with lavender vital oil were competent to increase weight at a normal rate. Though, the relative weight of their kidneys and liver did not rise irrepressibly.

Hence, their hemodynamics and metabolism were apparently stable. Finally, their liver and kidneys did not face oxidative stress.

Given these consequences, the scientists stated that the antioxidant effects of lavender oil allowed it to protect the liver and kidneys against oxidative damage.

Sources include

https://www.ncbi.nlm.nih.gov/pubmed/15557345

https://www.sciencedirect.com/science/article/pii/S0926669015002691

https://www.liebertpub.com/doi/10.1089/jmf.2014.0130

Seth Sale

Seth Sale is a seasoned journalist with nearly 10 years of experience. While studying journalism at the University of Tennessee, Seth found a passion for finding engaging stories. As a journalist to Top Health Journal, Seth mostly covers state and national developments. Contact Email: seth@tophealthjournal.com Phone: 720.907.1925

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