A recent study had reported increased risks of cardiac arrest among people who consume non-steroidal, anti-inflammatory drugs such as Ibuprofen and Diclofenac.
The study was led by the researchers at the Copenhagen University in Denmark. They examined the data of patients from the Danish Cardiac Arrest Registry. Three thousand Three hundred and seventy six patients were identified who took a painkiller thirty days before the health incident.
Fifty-one percent of the participants used Ibuprofen whereas, twenty-two percent of the patients used Diclofenac. The analytical results of the study showed that these painkillers were reported to increase the risks of heart attacks by thirty-one percent. In particular, Ibuprofen and Diclofenac were associated with a thirty-one percent and fifty percent increased odds of cardiac arrest, respectively.
The Cardiology Professor Gunnar H. Gislason stated that buying these drugs without a prescription or any advice from the doctor shows that these drugs are trusted among the general public. However, the findings of the study clearly show that NSAIDs are not always harmless. They must be used with caution. People suffering from cardiovascular diseases must avoid Ibuprofen and Diclofenac because they greatly put our heart’s health at risk. The results of the study were published in the journal Cardiovascular Pharmacotherapy.
The Danish study is just one in many of the researches that have established strong links between NSAIDs and cardiac issues.
Furthermore, a 2014 study revealed that NSAIDs were the potential cause behind the increased odds of 30-day stroke mortality. Data published in the journal Neurology found that stroke-related deaths were 19 percent higher in patients who took painkillers as compared to the nonusers.
In addition, a study published in the British Medical Journal found a causal relationship between painkillers and heart failure risks among older patients. The researchers examined 10 million patients across Europe including the Netherlands, U.K., Italy, and Germany. The participants were aged 77 years and older.
The research data showed that the use of painkillers was associated with a 19 percent increase in the risks associating the heart failure. However, the risk of heart failure varied with certain painkillers. Naproxen was found to cause a sixteen percent rise in heart-related issues while ketorolac was found to cause an eighty-three percent increase in the cardiac arrests. Ibuprofen and Diclofenac were reported to double the risks, however; the results didn’t hold any significance for the patients who were younger than 65 years old.
Prof. Peter Weissberg, Medical Director at the British Heart Foundation also added that NSAIDs are a group of drugs commonly taken by patients with joint problems but they increase the risk of developing heart failure. Since the heart and joint problems often coexist, particularly in older people, thus the doctors should consider carefully how they prescribe NSAIDs and are suggested to advise the lowest effective dose for the shortest possible time.
A 2013 study also showed that taking high doses of painkillers are responsible for every, one in three heart attacks. The findings were published in the journal The Lancet.
Owing to the facts stated in several studies, FDA has instructed the drug manufacturers to indicate the warnings related to heart attack and stroke on the labels of the painkillers.